SCHEMBL7202672

CCCC(=O)O[C@H]1[C@H](n2cnc3c(OC(=O)N(c4ccccc4)c4ccccc4)nc(NC(=O)C(C)C)nc32)O[C@H](COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)[C@]1(O)O[P@@](OCCC#N)N(C(C)C)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	TYMP	P19971	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6066317	1.00	TYMP (0.32)	TYMP
SCHEMBL313848	0.88	TYMP (0.36)	TYMP
SCHEMBL6360436	0.84	TYMP (0.32)	TYMP
SCHEMBL7714333	0.83	CDK5 (0.30)	—
SCHEMBL23827243	0.80	CDK5 (0.30)	—
SCHEMBL23827267	0.79	—	—
SCHEMBL23827202	0.79	—	—
SCHEMBL29657013	0.79	TYMP (0.46)	TYMP
SCHEMBL20394013	0.79	—	—
SCHEMBL8141933	0.76	TYMP (0.35)	TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2003100017-A2	OLIGONUCLEOTIDES HAVING MODIFIED NUCLEOSIDE UNITS	ISIS PHARMACEUTICALS, INC. (US)	2003-12-04	—	—	WO	disclosed