Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.69 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579928 | 0.88 | LSS (0.62) | LSSACHETACR3CYP11B1CYP11B2 | |
| SCHEMBL4801628 | 0.85 | LSS (0.81) | LSSACHELMNAL3MBTL1 | |
| SCHEMBL4801624 | 0.85 | LSS (0.81) | LSSACHELMNAL3MBTL1 | |
| SCHEMBL4800809 | 0.85 | LSS (0.78) | LSSACHETACR3LMNAL3MBTL1 | |
| SCHEMBL4800806 | 0.85 | LSS (0.78) | LSSACHETACR3LMNAL3MBTL1 | |
| SCHEMBL7203542 | 0.83 | LSS (0.61) | LSSACHECYP11B1CYP11B2LMNA | |
| SCHEMBL4428285 | 0.82 | LSS (1.00) | LSSACHE | |
| SCHEMBL4428287 | 0.82 | LSS (1.00) | LSSACHE | |
| SCHEMBL4808060 | 0.81 | LSS (0.69) | LSSACHETACR3CYP11B1CYP11B2 | |
| SCHEMBL4808068 | 0.81 | LSS (0.69) | LSSACHETACR3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |