Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 6/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6541878 | 1.00 | FFAR1 (0.44) | FFAR1PDE2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7202934 | 1.00 | FFAR1 (0.44) | FFAR1PDE2ACYP2D6SLC6A2SLC6A4 | |
| SCHEMBL7199745 | 0.87 | MEN1 (0.43) | CYP2D6SLC6A2SLC6A4KCNH2TACR1 | |
| SCHEMBL6540636 | 0.87 | MEN1 (0.43) | CYP2D6SLC6A2SLC6A4KCNH2TACR1 | |
| SCHEMBL7201086 | 0.87 | MEN1 (0.43) | CYP2D6SLC6A2SLC6A4KCNH2TACR1 | |
| SCHEMBL7193869 | 0.86 | KDM4E (0.48) | TACR1 | |
| SCHEMBL7193865 | 0.86 | KDM4E (0.48) | TACR1 | |
| SCHEMBL6540050 | 0.86 | KDM4E (0.48) | TACR1 | |
| Hydrochloric Acid SCHEMBL6541618 | 0.84 | MAPT (0.48) | CYP2D6SLC6A2SLC6A4KCNH2TACR1 | |
| Hydrochloric Acid SCHEMBL6541085 | 0.83 | KDM4E (0.51) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |