Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.32 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539812 | 0.92 | POLB (0.46) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL8658428 | 0.88 | POLB (0.49) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL15496851 | 0.87 | POLB (0.43) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL26451579 | 0.86 | POLB (0.39) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL15301590 | 0.86 | POLB (0.39) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL31380110 | 0.86 | POLB (0.39) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL26451573 | 0.86 | POLB (0.39) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL343674 | 0.86 | POLB (0.45) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL8667158 | 0.85 | POLB (0.47) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL22702494 | 0.85 | POLB (0.47) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203356-A1 | RNase L activator-antisense complexes | THE CLEVELAND CLINIC FOUNDATION (US) | 2003-10-30 | — | — | US | disclosed |
| US-6214805-B1 | GENES, GENE SIGNALS, GENOMES RNA STRANDS AND RESPIRATORY SYNCYTIAL VIRUS WITH PROMOTERS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-04-10 | — | — | US | disclosed |
| EP-1007655-A1 | RNASE L ACTIVATORS AND ANTISENSE OLIGONUCLEOTIDES EFFECTIVE TO TREAT RSV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (US) | 2000-06-14 | — | — | EP | disclosed |
| US-5998602-A | RNase L activators and antisense oligonucleotides effective to treat RSV infections | THE CLEVELAND CLINIC FOUINDATION AND GOVERNMENT (US) | 1999-12-07 | — | — | US | disclosed |