Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241265 | 0.92 | ESR1 (0.46) | KIF11HDAC8HDAC4HDAC2ACHE | |
| SCHEMBL129151 | 0.89 | HDAC8 (0.56) | KIF11HDAC8HDAC4HDAC2ACHE | |
| Water SCHEMBL29289408 | 0.86 | HDAC8 (0.54) | KIF11HDAC8HDAC4HDAC2ACHE | |
| Nitrogen SCHEMBL28547462 | 0.81 | HDAC8 (0.50) | KIF11HDAC8HDAC4HDAC2ACHE | |
| Methoxymethane SCHEMBL28022475 | 0.81 | HDAC8 (0.50) | KIF11HDAC8HDAC4HDAC2ACHE | |
| SCHEMBL8712101 | 0.80 | TSHR (0.52) | ALDH1A1L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL29002849 | 0.79 | HDAC8 (0.54) | KIF11HDAC8HDAC4HDAC2ACHE | |
| SCHEMBL28653353 | 0.79 | HDAC8 (0.54) | KIF11HDAC8HDAC4HDAC2ACHE | |
| SCHEMBL9492395 | 0.79 | HDAC8 (0.54) | KIF11HDAC8HDAC4HDAC2ACHE | |
| SCHEMBL28328740 | 0.79 | HDAC8 (0.54) | KIF11HDAC8HDAC4HDAC2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068832-A1 | CUREABLE SILANE FUNCTIONALIZED SEALANT COMPOSITION AND MANUFACTURE OF SAME | BRIDGESTONE CORPORATION (JP) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068832-A1 | CUREABLE SILANE FUNCTIONALIZED SEALANT COMPOSITION AND MANUFACTURE OF SAME | BRIDGESTONE CORPORATION (JP) | 2003-08-21 | — | — | WO | disclosed |