⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphorylethanolamine SCHEMBL20798002 | 0.97 | LPAR3 (0.46) | — | |
| Phosphorylethanolamine SCHEMBL44347 | 0.97 | — | — | |
| Phosphorylethanolamine SCHEMBL31158295 | 0.97 | — | — | |
| Phosphorylethanolamine SCHEMBL30169660 | 0.94 | — | — | |
| Phosphorylethanolamine SCHEMBL29598224 | 0.94 | LPAR3 (0.44) | — | |
| Phosphorylethanolamine SCHEMBL9802188 | 0.94 | LPAR3 (0.44) | — | |
| Phosphorylethanolamine SCHEMBL9801949 | 0.94 | LPAR3 (0.44) | — | |
| Phosphorylethanolamine SCHEMBL8341244 | 0.94 | — | — | |
| Phosphorylethanolamine SCHEMBL10724664 | 0.94 | — | — | |
| Phosphorylethanolamine SCHEMBL29903196 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030165575-A1 | Methods and compositions for treatment and diagnosis of alzheimer disease and other disorders | RESEARCH FOUNDATION FOR MENTAL HYGEINE, INC. | 2003-09-04 | — | — | US | disclosed |
| WO-1995019178-A1 | METHODS AND COMPOSITIONS FOR TREATMENT AND DIAGNOSIS OF ALZHEIMER DISEASE AND OTHER DISORDERS | RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (US) | 1995-07-20 | — | — | WO | disclosed |