SCHEMBL7203299

SCHEMBL7203299

CCCCCN(C)CCCCCCOC1CCC(N(Cc2cc(F)c(F)cc2F)C(=O)OCc2ccccc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 19/20 0.49
PTGDR2 Q9Y5Y4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7203301 1.00 HTR2A (0.49) HTR2APTGDR2
SCHEMBL4804638 0.94 HTR2A (0.49) HTR2APTGDR2
SCHEMBL4804645 0.94 HTR2A (0.49) HTR2APTGDR2
SCHEMBL5015811 0.93 HTR2A (0.48) HTR2APTGDR2
SCHEMBL4809045 0.93 HTR2A (0.48) HTR2APTGDR2
SCHEMBL4797738 0.92 HTR2A (0.49) HTR2APTGDR2
SCHEMBL4797733 0.92 HTR2A (0.49) HTR2APTGDR2
SCHEMBL4806970 0.90 HTR2A (0.47) HTR2APTGDR2
SCHEMBL4806966 0.90 HTR2A (0.47) HTR2APTGDR2
SCHEMBL7206805 0.89 HTR2A (0.41) HTR2APTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1311475-A1 NOVEL AMINOCYCLOHEXANE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-05-21 EP disclosed
WO-2002014267-A1 NOVEL AMINOCYCLOHEXANE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2002-02-21 WO disclosed