Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8888237 | 0.96 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL36527 | 0.96 | — | — | |
| Acetic Acid SCHEMBL17909908 | 0.96 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL139024 | 0.96 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL1879030 | 0.96 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL2516097 | 0.96 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL1578192 | 0.96 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL7784606 | 0.96 | FFAR3 (0.64) | — | |
| Acetic Acid SCHEMBL28708640 | 0.92 | — | — | |
| Acetic Acid SCHEMBL21542485 | 0.92 | FFAR3 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566066-B1 | Nucleotide sequences coding polypeptide for use in the diagnosis, treatment and prevention of diabetes and pancreatic defects | INCYTE GENOMICS, INC. | 2003-05-20 | — | — | US | disclosed |