Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromoethanamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoethanamine SCHEMBL67614 | 0.95 | — | — | |
| Bromoethanamine SCHEMBL9658147 | 0.95 | — | — | |
| Bromoethanamine SCHEMBL28859568 | 0.90 | — | — | |
| Bromoethanamine SCHEMBL94211 | 0.89 | — | — | |
| Bromoethanamine SCHEMBL27320074 | 0.84 | — | — | |
| Bromoethanamine SCHEMBL217318 | 0.84 | — | — | |
| Bromoethanamine SCHEMBL11788853 | 0.84 | — | — | |
| Bromoethanamine SCHEMBL3129998 | 0.80 | — | — | |
| Bromoethanamine SCHEMBL28852644 | 0.76 | — | — | |
| Dioxane SCHEMBL177060 | 0.73 | TTR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607710-B1 | Provide a bisphosphonic acid derivative and said bisphosphonic acid derivative being labeled with a radioactive nuclide, which has properties of rapid accumulation to the bone and rapid urinary excretion. | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1092723-A2 | Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |