Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203726 | 0.87 | MEN1 (0.53) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL27760026 | 0.86 | MEN1 (0.52) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7200601 | 0.86 | MEN1 (0.65) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7203205 | 0.86 | MAPT (0.58) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7206304 | 0.86 | MEN1 (0.52) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7206032 | 0.86 | MAPT (0.52) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7199122 | 0.84 | MEN1 (0.51) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7200422 | 0.84 | MAPT (0.51) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7200293 | 0.83 | MEN1 (0.50) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7207794 | 0.82 | MEN1 (0.49) | KDM4EMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6310049-B1 | 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1104418-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-06-06 | — | — | EP | disclosed |
| WO-2000009500-A2 | NEMATICIDAL PYRAZOLES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | KDM4E 2628/4885MAPT 4683/4885MEN1 4820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.