Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074643 | 1.00 | ADRB3 (0.62) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074650 | 1.00 | ADRB3 (0.62) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074487 | 0.92 | ADRB3 (0.62) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL7178919 | 0.92 | ADRB3 (0.62) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074479 | 0.92 | ADRB3 (0.62) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074579 | 0.89 | ADRB3 (0.76) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6074581 | 0.89 | ADRB3 (0.76) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL7198604 | 0.79 | ADRB3 (0.61) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL6872047 | 0.78 | ADRB3 (0.80) | ADRB3ADRB2ADRB1MEN1CYP1A2 | |
| SCHEMBL7220467 | 0.78 | ADRB3 (0.80) | ADRB3ADRB2ADRB1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301482-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006232-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |