Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201915 | 0.82 | CYP1A2 (0.37) | — | |
| SCHEMBL6436861 | 0.81 | CYP1A2 (0.34) | — | |
| SCHEMBL7930433 | 0.74 | CYP11B1 (0.33) | CYP11B2 | |
| Hydrochloric Acid SCHEMBL6287696 | 0.74 | PTPN1 (0.35) | KDM1AMAPTKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7807224 | 0.74 | PTPN1 (0.35) | KDM1AMAPTKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8584663 | 0.74 | PTPN1 (0.35) | KDM1AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8020332 | 0.74 | PTPN1 (0.35) | KDM1AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7206931 | 0.73 | GSTP1 (0.34) | MAPTKDM4EALDH1A1HPGDNISCH | |
| Hydrochloric Acid SCHEMBL6283798 | 0.73 | PTPN1 (0.34) | KDM1AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7036428 | 0.72 | MAPT (0.38) | MAPTKDM4EALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775148-B2 | BISCYCLOPENTADIENYL DIENE COMPLEXES | DOW CHEMICAL CO (US) | 2003-01-02 | — | — | EP | claimed |
| US-6465384-B1 | BISCYCLOPENTADIENYL GROUP 4 TRANSITION METAL COMPLEXES POSSESSING DIENE LIGANDS AND TO USE AS POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY | 2002-10-15 | — | — | US | claimed |
| US-5972822-A | Biscyclopentadienyldiene complex containing addition polymerization catalysts | THE DOW CHEMICAL COMPANY (US) | 1999-10-26 | — | — | US | claimed |
| EP-0775148-B1 | BISCYCLOPENTADIENYL DIENE COMPLEXES | DOW CHEMICAL CO (US) | 1999-08-25 | — | — | EP | claimed |
| EP-0775148-A1 | BISCYCLOPENTADIENYL DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1997-05-28 | — | — | EP | claimed |
| US-5616664-A | Polymerization process with biscyclopentadienyl diene complex containing catalysts | THE DOW CHEMICAL COMPANY (US) | 1997-04-01 | — | — | US | claimed |
| WO-1996004290-A1 | BISCYCLOPENTADIENYL DIENE COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1996-02-15 | — | — | WO | claimed |
| EP-0915098-A2 | Biscyclopentadienyl diene complexes, their preparation and catalyst compositions containing them | THE DOW CHEMICAL COMPANY (US) | 1999-05-12 | — | — | EP | disclosed |