SCHEMBL7203787

SCHEMBL7203787

Cc1cccc(Cc2nnc(C(=O)[C@@H](NC(=O)Cn3c(-c4ccc(F)cc4)nccc3=O)C(C)C)o2)c1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7003495 0.87 ELANE (1.00) ELANE
SCHEMBL7003169 0.87 ELANE (1.00) ELANE
SCHEMBL3050184 0.87 ELANE (1.00) ELANE
SCHEMBL29706324 0.87 ELANE (1.00) ELANE
SCHEMBL7199744 0.84 ELANE (0.79) ELANE
SCHEMBL7203045 0.83 ELANE (0.82) ELANE
SCHEMBL3049885 0.82 ELANE (0.75) ELANE
SCHEMBL8491066 0.82 ELANE (0.75) ELANE
SCHEMBL7005501 0.81 ELANE (1.00) ELANE
SCHEMBL7199749 0.81 ELANE (1.00) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656911-B2 Oxadiazole ring structure peptoids which are useful as inhibitors of serine proteases CORTECH, INC. 2003-12-02 US claimed
US-20030203851-A1 Substituted oxadiazole, peptoids which are useful for treating adult respiratory distress syndrome, septic shock and myocardial ischemia-reperfusion injury CORTECH, INC. 2003-10-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030203851-A1 Substituted oxadiazole, peptoids which are useful for treating adult respiratory distress syndrome, septic shock and myocardial ischemia-reperfusion injury TNNI3, PEPD, STK35 ELANE 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.