Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 9/20 | 0.51 |
| ▸ | HTR2A | P28223 | 8/20 | 0.49 |
| ▸ | HTR2C | P28335 | 7/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LIPC | P11150 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203921 | 1.00 | LSS (0.51) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL7205298 | 0.98 | LSS (0.51) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL7205301 | 0.98 | LSS (0.51) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4804941 | 0.93 | LSS (0.52) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4804944 | 0.93 | LSS (0.52) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4798065 | 0.91 | LSS (0.53) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4798074 | 0.91 | LSS (0.53) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4805711 | 0.90 | LSS (0.53) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4805715 | 0.90 | LSS (0.53) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL7209472 | 0.89 | LSS (0.41) | LSSHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |