Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6541607 | 0.99 | KDM4E (0.49) | KDM4EALDH1A1TDP1CCR5TACR1 | |
| Hydrochloric Acid SCHEMBL7191248 | 0.99 | KDM4E (0.49) | KDM4EALDH1A1TDP1CCR5TACR1 | |
| Hydrochloric Acid SCHEMBL7191245 | 0.99 | KDM4E (0.49) | KDM4EALDH1A1TDP1CCR5TACR1 | |
| SCHEMBL6541486 | 0.89 | MAPT (0.51) | KDM4EALDH1A1TACR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6540428 | 0.89 | MAPT (0.50) | KDM4EALDH1A1TACR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7194019 | 0.89 | MAPT (0.50) | KDM4EALDH1A1TACR1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6541012 | 0.89 | TACR1 (0.59) | TACR1 | |
| Hydrochloric Acid SCHEMBL7194013 | 0.89 | MAPT (0.50) | KDM4EALDH1A1TACR1KMT2AMEN1 | |
| SCHEMBL7193865 | 0.88 | KDM4E (0.48) | KDM4ETACR1KMT2AMEN1 | |
| SCHEMBL6540050 | 0.88 | KDM4E (0.48) | KDM4ETACR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |