Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.76 |
| ▸ | TMIGD3 | P0DMS9 | 5/20 | 0.76 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.63 |
| ▸ | CDK1 | P06493 | 2/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PI4KA | P42356 | 1/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209250 | 0.90 | ADORA2A (0.69) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL7209277 | 0.89 | ADORA2A (0.80) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL5162419 | 0.88 | ADORA2A (0.82) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL7212614 | 0.88 | ADORA2A (0.72) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL2060290 | 0.88 | ADORA2A (0.65) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL7204756 | 0.87 | PDE4A (0.65) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL17802554 | 0.87 | ADORA2A (0.78) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL7209489 | 0.87 | ADORA2A (0.61) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL7205096 | 0.87 | ADORA2A (0.61) | ADORA2AADORA1TMIGD3ADORA2BCDK1 | |
| SCHEMBL7209426 | 0.86 | PDE4A (0.60) | ADORA2AADORA1TMIGD3ADORA2BCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |