Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.58 |
| ▸ | PGK1 | P00558 | 1/20 | 0.52 |
| ▸ | PGK2 | P07205 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7209484 | 0.96 | ADORA2A (0.56) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7204211 | 0.91 | ADORA2A (0.55) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7209494 | 0.91 | ADORA2A (0.52) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7207833 | 0.90 | ADORA2A (0.71) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7209488 | 0.90 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7208887 | 0.90 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7588051 | 0.89 | ADORA2A (0.53) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7201970 | 0.89 | ADORA2A (0.53) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7204188 | 0.89 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7206736 | 0.89 | ADORA2A (0.59) | ADORA2AADORA3ADORA2BADORA1PGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610665-B1 | Treatment of inflammatory diseases, asthma or chronic obstructive pulmonary disease | SMITHKLINE BEECHAM CORPORATION | 2003-08-26 | — | — | US | claimed |
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | claimed |