Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 8/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 4/20 | 0.31 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204663 | 1.00 | LSS (0.44) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7205517 | 0.96 | LSS (0.43) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7205514 | 0.96 | LSS (0.43) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7210492 | 0.89 | LSS (0.35) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7210491 | 0.89 | LSS (0.35) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4807923 | 0.83 | LSS (0.44) | LSS | |
| SCHEMBL4807917 | 0.83 | LSS (0.44) | LSS | |
| SCHEMBL27578351 | 0.83 | LSS (0.43) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27578352 | 0.83 | LSS (0.43) | LSSCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL4803635 | 0.80 | LSS (0.49) | LSSCHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100455566-C | Novel derivatives of aminocyclohexane | HOFFMANN LA ROCHE (CH) | 2009-01-28 | — | — | CN | disclosed |
| CN-1468214-A | Novel derivatives of aminocyclohexane | - | 2004-01-14 | — | — | CN | disclosed |
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |