Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212493 | 0.88 | ADORA2A (0.47) | ADORA2AADORA1TLR7MAPK1PNP | |
| SCHEMBL2060321 | 0.87 | ADORA2A (0.46) | ADORA2AADORA1TLR7MAPK1PNP | |
| SCHEMBL14944613 | 0.87 | ADORA2A (0.46) | ADORA2AADORA1TLR7MAPK1PNP | |
| SCHEMBL19370095 | 0.86 | ADORA2A (0.45) | ADORA2AADORA1TLR7MAPK1PNP | |
| SCHEMBL5730944 | 0.86 | TLR7 (0.55) | ADORA2AADORA1TLR7MAPK1ALDH1A1 | |
| SCHEMBL5731043 | 0.85 | ADORA1 (0.47) | ADORA2AADORA1TLR7MAPK1PNP | |
| SCHEMBL5731379 | 0.85 | TLR7 (0.45) | ADORA2AADORA1TLR7MAPK1PNP | |
| SCHEMBL5731620 | 0.85 | ADORA2A (0.59) | ADORA2AADORA1TLR7MAPK1 | |
| SCHEMBL2060517 | 0.85 | TLR7 (0.45) | ADORA2AADORA1TLR7MAPK1PNP | |
| SCHEMBL7209948 | 0.83 | TSHR (0.52) | ADORA2AADORA1TLR7MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |