Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.64 |
| ▸ | HTR2A | P28223 | 7/20 | 0.49 |
| ▸ | HTR2C | P28335 | 6/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205251 | 1.00 | LSS (0.64) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL7205049 | 0.94 | LSS (0.62) | LSSHTR2AHTR2C | |
| SCHEMBL7205048 | 0.94 | LSS (0.62) | LSSHTR2AHTR2C | |
| SCHEMBL4804550 | 0.93 | LSS (0.74) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4804540 | 0.93 | LSS (0.74) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4800512 | 0.92 | LSS (0.62) | LSSHTR2AHTR2C | |
| SCHEMBL4800506 | 0.92 | LSS (0.62) | LSSHTR2AHTR2C | |
| SCHEMBL4806110 | 0.92 | LSS (0.72) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4806121 | 0.92 | LSS (0.72) | LSSHTR2AHTR2CTBXA2RPTGDR | |
| SCHEMBL4804822 | 0.90 | LSS (0.62) | LSSHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |