Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205649 | 1.00 | CCR1 (0.61) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL14419959 | 0.93 | CCR1 (0.66) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL13824477 | 0.93 | CCR1 (0.66) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL13824474 | 0.91 | CCR1 (0.53) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL7206934 | 0.91 | CCR1 (0.64) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL7206932 | 0.91 | CCR1 (0.64) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL7206191 | 0.90 | CCR1 (0.57) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL7206194 | 0.90 | CCR1 (0.57) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL18895949 | 0.90 | CCR1 (0.65) | CCR1CHRM2CCR5OPRM1OPRL1 | |
| SCHEMBL10287601 | 0.90 | CCR1 (0.63) | CCR1CHRM2CCR5DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613905-B1 | Treating or preventing a disease associated with aberrant leukocyte recruitment and/or activation | MILLENNIUM PHARMACEUTICALS, INC. | 2003-09-02 | — | — | US | disclosed |