Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 3/20 | 0.40 |
| ▸ | XIAP | P98170 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205927 | 1.00 | HTT (0.55) | HTTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6541329 | 1.00 | HTT (0.55) | HTTMEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7200288 | 0.87 | TACR1 (0.46) | HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6540431 | 0.87 | TACR1 (0.46) | HTTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7200284 | 0.87 | TACR1 (0.46) | HTTMEN1KMT2A | |
| SCHEMBL7194671 | 0.84 | TACR1 (0.45) | MEN1KMT2ASLC6A4KDM1AMAOA | |
| SCHEMBL7194679 | 0.84 | TACR1 (0.45) | MEN1KMT2ASLC6A4KDM1AMAOA | |
| SCHEMBL6540752 | 0.84 | TACR1 (0.45) | MEN1KMT2ASLC6A4KDM1AMAOA | |
| SCHEMBL7204313 | 0.83 | TACR1 (0.42) | HTTMEN1KMT2A | |
| SCHEMBL7204308 | 0.83 | TACR1 (0.42) | HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294700-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000631-A2 | BENZHYDRYL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |