Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205973 | 1.00 | LSS (0.54) | LSSACHECYP11B1CYP11B2KCNH2 | |
| SCHEMBL7206570 | 0.88 | LSS (0.69) | LSSACHECYP11B1CYP11B2 | |
| SCHEMBL7206572 | 0.88 | LSS (0.69) | LSSACHECYP11B1CYP11B2 | |
| SCHEMBL4804741 | 0.88 | LSS (0.61) | LSSACHECYP11B1CYP11B2SLC6A5 | |
| SCHEMBL4804745 | 0.88 | LSS (0.61) | LSSACHECYP11B1CYP11B2SLC6A5 | |
| SCHEMBL4808075 | 0.85 | LSS (0.52) | LSSACHECYP11B1CYP11B2 | |
| SCHEMBL4808082 | 0.85 | LSS (0.52) | LSSACHECYP11B1CYP11B2 | |
| SCHEMBL4799121 | 0.84 | LSS (0.70) | LSSACHE | |
| SCHEMBL4799116 | 0.84 | LSS (0.70) | LSSACHE | |
| SCHEMBL4809994 | 0.82 | LSS (0.71) | LSSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |