Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 7/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205076 | 1.00 | EPHX2 (0.40) | EPHX2KDM5AKDM4CKDM5CKDM5B | |
| SCHEMBL7209836 | 0.99 | EPHX2 (0.39) | EPHX2KDM5AKDM4CKDM5CKDM5B | |
| SCHEMBL14671046 | 0.85 | SMN1; SMN2 (0.45) | EPHX2GAASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4807006 | 0.83 | LSS (0.53) | LSS | |
| SCHEMBL4808632 | 0.83 | LSS (0.53) | LSS | |
| SCHEMBL4806262 | 0.82 | LSS (0.54) | LSS | |
| SCHEMBL17592061 | 0.78 | GAA (0.47) | EPHX2GAASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL17592354 | 0.78 | GAA (0.47) | EPHX2GAASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7211437 | 0.78 | EPHX2 (0.34) | EPHX2KDM5AKDM4CKDM5CKDM5B | |
| SCHEMBL7211441 | 0.78 | EPHX2 (0.34) | EPHX2KDM5AKDM4CKDM5CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |