Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 8/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206842 | 1.00 | PDE4D (0.61) | PDE4DPDE4APDE4BPDE4CCHEK1 | |
| SCHEMBL7212832 | 0.89 | PDE4D (0.63) | PDE4DPDE4APDE4BPDE4CKDM1A | |
| SCHEMBL11840218 | 0.87 | PDE4D (0.76) | PDE4DPDE4APDE4BPDE4CPDE3A | |
| SCHEMBL11840227 | 0.87 | PDE4D (0.76) | PDE4DPDE4APDE4BPDE4CPDE3A | |
| SCHEMBL11840097 | 0.87 | PDE4D (0.65) | PDE4DPDE4APDE4BPDE4CPDE3A | |
| SCHEMBL11840105 | 0.87 | PDE4D (0.65) | PDE4DPDE4APDE4BPDE4CPDE3A | |
| SCHEMBL11844968 | 0.86 | PDE4D (0.64) | PDE4DPDE4APDE4BPDE4CPDE3A | |
| SCHEMBL7319066 | 0.86 | PDE4D (0.64) | PDE4DPDE4APDE4BPDE4CCHEK1 | |
| SCHEMBL7367489 | 0.86 | PDE4D (0.64) | PDE4DPDE4APDE4BPDE4CCHEK1 | |
| SCHEMBL11844955 | 0.86 | PDE4D (0.64) | PDE4DPDE4APDE4BPDE4CPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968211-B1 | TETRAZOLE DERIVATIVES | ALTANA PHARMA AG (DE) | 2003-08-27 | — | — | EP | disclosed |
| US-6143759-A | ANTIINFLAMMATORY AGENTS AND ANTICOAGULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-11-07 | — | — | US | disclosed |