Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978028 | 0.81 | KMT2A (0.62) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL11360894 | 0.81 | KMT2A (0.62) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL17975323 | 0.81 | KMT2A (0.62) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL11360897 | 0.81 | KMT2A (0.62) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL258450 | 0.80 | KMT2A (0.63) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL1957446 | 0.79 | KMT2A (0.60) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL291297 | 0.79 | KMT2A (0.60) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL17988274 | 0.78 | KMT2A (0.78) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL2681858 | 0.78 | KMT2A (0.78) | KMT2ATDP1POLBL3MBTL1MEN1 | |
| SCHEMBL11429809 | 0.78 | KMT2A (0.58) | KMT2ATDP1POLBL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | claimed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | claimed |
| EP-0922050-B1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2003-07-30 | — | — | EP | disclosed |
| EP-0922050-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5750510-A | ANTIBIOTICS | ABBOTT LABORATORIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997042205-A1 | 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1997-11-13 | — | — | WO | disclosed |