Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.64 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203542 | 0.96 | LSS (0.61) | LSSGPR119ACHE | |
| SCHEMBL27578319 | 0.89 | LSS (0.59) | LSSGPR119 | |
| SCHEMBL6019198 | 0.88 | LSS (0.48) | LSSGPR119ACHE | |
| SCHEMBL6019193 | 0.88 | LSS (0.48) | LSSGPR119ACHE | |
| SCHEMBL6020052 | 0.85 | LSS (0.57) | LSSGPR119ACHE | |
| SCHEMBL6019091 | 0.85 | LSS (0.48) | LSSGPR119ACHE | |
| SCHEMBL6019087 | 0.85 | LSS (0.48) | LSSGPR119ACHE | |
| SCHEMBL6020056 | 0.85 | LSS (0.57) | LSSGPR119ACHE | |
| SCHEMBL4803079 | 0.84 | LSS (0.76) | LSSACHE | |
| SCHEMBL4801793 | 0.84 | LSS (0.76) | LSSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |