Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 3/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210755 | 1.00 | CHRM2 (0.35) | CHRM2S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL7209024 | 1.00 | CHRM2 (0.35) | CHRM2S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL7210752 | 1.00 | CHRM2 (0.35) | CHRM2S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL7207712 | 1.00 | CHRM2 (0.35) | CHRM2S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL7209027 | 1.00 | CHRM2 (0.35) | CHRM2S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL7211441 | 0.98 | EPHX2 (0.34) | CHRM2S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL7211437 | 0.98 | EPHX2 (0.34) | CHRM2S1PR2S1PR1S1PR3S1PR5 | |
| SCHEMBL4800948 | 0.87 | CHRM2 (0.34) | CHRM2LSS | |
| SCHEMBL4800942 | 0.87 | CHRM2 (0.34) | CHRM2LSS | |
| SCHEMBL4805020 | 0.82 | LSS (0.49) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |