Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAT1 | P21673 | 1/20 | 0.74 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201037 | 1.00 | SAT1 (0.74) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7202965 | 1.00 | SAT1 (0.74) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7203886 | 0.97 | SAT1 (0.70) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7199454 | 0.94 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7202980 | 0.94 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7207732 | 0.94 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7206783 | 0.94 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7201201 | 0.94 | SAT1 (0.67) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL10045082 | 0.89 | SAT1 (0.96) | SAT1GNAI3GNAO1GNAI1HDAC3 | |
| SCHEMBL7205993 | 0.89 | SAT1 (0.61) | SAT1GNAI3GNAO1GNAI1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605645-B2 | Such as 1,15-di(cyclopropylmethylamino)-8-benzyl-4,8,12-triazapentadecane; carcinostatic action | RIKEN (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020067472-A1 | Linear polyamine compounds and polyamine anticancer agents | IWATA MASAAKI (JP) | 2002-06-06 | — | — | US | disclosed |
| US-6319956-B1 | N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. | RIKEN (JP) | 2001-11-20 | — | — | US | disclosed |