Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.42 |
| ▸ | PGK1 | P00558 | 3/20 | 0.41 |
| ▸ | PGK2 | P07205 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7204041 | 0.97 | ADORA2A (0.48) | ADORA2AADORA3ADORA2BPGK1PGK2 | |
| Formic Acid SCHEMBL7202921 | 0.93 | ADORA2A (0.47) | ADORA2AADORA3ADORA2BPGK1PGK2 | |
| SCHEMBL7207906 | 0.92 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BPGK1PGK2 | |
| SCHEMBL7207903 | 0.91 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BPGK1PGK2 | |
| SCHEMBL7208447 | 0.89 | ADORA2A (0.47) | ADORA2AADORA3ADORA2BPGK1PGK2 | |
| SCHEMBL7204152 | 0.87 | ADORA2A (0.47) | ADORA2AADORA3ADORA2BPGK1PGK2 | |
| Formic Acid SCHEMBL7202168 | 0.87 | ADORA2A (0.46) | ADORA2AADORA3ADORA2B | |
| Formic Acid SCHEMBL7207390 | 0.86 | ADORA2A (0.52) | ADORA2AADORA3ADORA2B | |
| SCHEMBL6835046 | 0.86 | ADORA2A (0.49) | ADORA2AADORA3ADORA2BPGK1PGK2 | |
| Formic Acid SCHEMBL7230638 | 0.85 | ADORA2A (0.47) | ADORA2AADORA3ADORA2BPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610665-B1 | Treatment of inflammatory diseases, asthma or chronic obstructive pulmonary disease | SMITHKLINE BEECHAM CORPORATION | 2003-08-26 | — | — | US | disclosed |
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | disclosed |