Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14382693 | 0.94 | CYP2D6 (0.57) | CYP2D6KCNH2PPARGPPARATSHR | |
| SCHEMBL17509790 | 0.91 | PPARA (0.68) | CYP2D6KCNH2PPARGPPARATSHR | |
| SCHEMBL9492166 | 0.91 | PPARA (0.68) | CYP2D6KCNH2PPARGPPARATSHR | |
| SCHEMBL8053831 | 0.90 | CYP2D6 (0.56) | CYP2D6KCNH2PPARGPPARAGGPS1 | |
| SCHEMBL3025896 | 0.90 | CYP4F2 (0.61) | CYP2D6KCNH2PPARGPPARAGGPS1 | |
| SCHEMBL9621361 | 0.90 | CYP2D6 (0.53) | CYP2D6KCNH2PPARGPPARATSHR | |
| SCHEMBL2911039 | 0.90 | TAAR1 (0.62) | CYP2D6KCNH2PPARGPPARATSHR | |
| SCHEMBL9827395 | 0.90 | CYP2D6 (0.53) | CYP2D6KCNH2PPARGPPARATSHR | |
| SCHEMBL3964532 | 0.89 | TSHR (0.60) | CYP2D6KCNH2PPARGPPARATSHR | |
| SCHEMBL4568871 | 0.89 | PPARA (0.61) | CYP2D6KCNH2PPARGPPARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258347-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-09-04 | — | — | US | claimed |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | claimed |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | claimed |
| US-8541625-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20130164803-A9 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | UNIVERSITY OF GEORGE RESEARCH FOUNDATION, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-8426649-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120295318-A1 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | UNIVERSITY OF GEORGE RESEARCH FOUNDATION, INC. (US) | 2012-11-22 | — | — | US | disclosed |
| US-8258347-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295318-A1 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | WEE1, WEE2, MPI | CYP2D6 528/4885KCNH2 3127/4885PPARG 2268/4885 |
| US-20130164803-A9 | CYCLOPROPENONES AND THE PHOTOCHEMICAL GENERATION OF CYCLIC ALKYNES THEREFROM | WEE1, WEE2, MPI | CYP2D6 528/4885KCNH2 3127/4885PPARG 2268/4885 |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | CYP2D6 528/4885KCNH2 3127/4885PPARG 2268/4885 |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | CYP2D6 528/4885KCNH2 3127/4885PPARG 2268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.