Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208051 | 1.00 | CCR1 (0.56) | CCR1CHRM2CCR5KDM4EALDH1A1 | |
| SCHEMBL7212461 | 0.92 | CCR1 (0.62) | CCR1CHRM2CCR5KDM4EALDH1A1 | |
| SCHEMBL7212465 | 0.92 | CCR1 (0.62) | CCR1CHRM2CCR5KDM4EALDH1A1 | |
| SCHEMBL10287559 | 0.91 | CCR1 (0.56) | CCR1CHRM2CCR5ALDH1A1DRD2 | |
| SCHEMBL10288256 | 0.91 | CCR1 (0.57) | CCR1CHRM2CCR5ALDH1A1DRD2 | |
| SCHEMBL10288255 | 0.91 | CCR1 (0.58) | CCR1CHRM2CCR5KDM4EDRD2 | |
| SCHEMBL13620909 | 0.91 | CCR1 (0.58) | CCR1CHRM2CCR5KDM4EDRD2 | |
| SCHEMBL10287589 | 0.90 | CCR1 (0.57) | CCR1CHRM2CCR5ALDH1A1DRD2 | |
| SCHEMBL13824392 | 0.90 | CCR1 (0.56) | CCR1CHRM2CCR5ALDH1A1DRD2 | |
| SCHEMBL14579625 | 0.90 | CCR1 (0.57) | CCR1CHRM2CCR5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613905-B1 | Treating or preventing a disease associated with aberrant leukocyte recruitment and/or activation | MILLENNIUM PHARMACEUTICALS, INC. | 2003-09-02 | — | — | US | disclosed |