SCHEMBL7208110

SCHEMBL7208110

CCCCCCC(C)(C)OC(C)(C)CCCCCC

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
GGPS1 O95749 6/20 0.39
SMPD1 P17405 5/20 0.39
FDPS P14324 9/20 0.38
CES2 O00748 1/20 0.37
LPAR1 Q92633 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26106465 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL11700902 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL20299931 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL2883813 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL9005784 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL6658765 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL20299935 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL11696332 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL11699499 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL17124832 1.00 TSHR (0.44) TSHRTHRBGGPS1SMPD1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963367-B1 PROCESS FOR PREPARING ALKYL ETHERS AND MIXTURES THEREOF FORTUM OIL & GAS OY (FI) 2002-07-24 EP claimed
EP-0964849-B1 SULFONYL UREA DERIVATIVES AND THEIR USE IN THE CONTROL OF INTERLEUKIN-1 ACTIVITY PFIZER (US) 2003-06-04 EP disclosed
EP-0812838-B1 PYRIDONECARBOXYLIC ACID DERIVATIVE SUBSTITUTED BY BICYCLIC AMINO GROUP, ESTER THEREOF, SALT THEREOF, AND BICYCLIC AMINE AS INTERMEDIATE THEREFOR DAINIPPON PHARMACEUTICAL CO (JP) 2002-05-02 EP disclosed
US-5990106-A ANTIBIOTICS; 3-AZABICYCLO(3.2.0)HEPT-3-YL GROUP JOINED AT GIVEN POSITION OF A PYRIDONECARBOXYLIC ACID RESIDUE, SUCH AS 7-(1-AMINO-3-AZABICYCLO(3.2.0)HEPT-3-YL)-1-CYCLOPROPYL-6,8-DIFLUORO-1,4 -DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1999-11-23 US disclosed
US-5633248-A GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS, DIARYLALKYLIDENEDIAMINES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-27 US disclosed
US-5594154-A 5-AMINO-2-BROMOMETHYL-2,4,6,7-TETRAMETHYL-2,3-DIHYDROBENZO(B) FURANS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-01-14 US disclosed
EP-0714893-A1 2-substituted benzothiazole derivatives useful in the treatment of diabetic complications GRELAN PHARMACEUTICAL CO., LTD. (JP) 1996-06-05 EP disclosed
US-5492929-A ENZYME INHIBITORS, ANTICHOLESTEROL AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-20 US disclosed
US-5391571-A Cholesterol ester hydrolase inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 1995-02-21 US disclosed
US-5329017-A Reduction of cyclopropane acrylic esters, sulfinic acid intermediate ROUSSEL-UCLAF (FR) 1994-07-12 US disclosed
US-5089511-A Trifluoromethylvinyl compounds ROUSSEL UCLAF (FR) 1992-02-18 US disclosed
US-5008281-A Insecticides, miticides, nematocides ROUSSEL UCLAF (FR) 1991-04-16 US disclosed
US-4925862-A PESTICIDES ROUSSEL UCLAF (FR) 1990-05-15 US disclosed
EP-0284005-A2 Method of production of polyolefins IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1988-09-28 EP disclosed
US-4689342-A MITICIDES, NEMATOCIDES ROUSSEL UCLAF (FR) 1987-08-25 US disclosed
US-4686224-A Oxindole antiinflammatory agents PFIZER INC. (US) 1987-08-11 US disclosed
US-4609650-A ANTIANDROGENS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-09-02 US disclosed
US-4603208-A MODIFIED POLYISOPRENE CONVERTED TO DOLICHOLS KURARAY CO., LTD. (JP) 1986-07-29 US disclosed
US-4388312-A HYPOTENSIVE AGENTS, ANTIALLERGENS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1983-06-14 US disclosed
US-4371725-A Process for the preparation of tertiary olefins and n-alkanols EC ERDOLCHEMIE GMBH (DE) 1983-02-01 US disclosed