Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.52 |
| ▸ | CDK2 | P24941 | 4/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.46 |
| ▸ | CDK1 | P06493 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.46 |
| ▸ | CCND1 | P24385 | 3/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208424 | 1.00 | ADORA2A (0.52) | ADORA2ACDK2CCNB2CCNE2CDK1 | |
| Formic Acid SCHEMBL7202128 | 0.96 | ADORA2A (0.51) | ADORA2ACDK2CCNB2CCNE2CDK1 | |
| Formic Acid SCHEMBL7202139 | 0.96 | ADORA2A (0.51) | ADORA2ACDK2CCNB2CCNE2CDK1 | |
| SCHEMBL7204932 | 0.93 | ADORA2A (0.51) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7207428 | 0.92 | ADORA2A (0.51) | ADORA2ACDK2CCNB2CCNE2CDK1 | |
| SCHEMBL7207432 | 0.92 | ADORA2A (0.51) | ADORA2ACDK2CCNB2CCNE2CDK1 | |
| SCHEMBL7202131 | 0.91 | ADORA2A (0.47) | ADORA2ACDK2CCNB2CCNE2CDK1 | |
| Formic Acid SCHEMBL7574645 | 0.90 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7202130 | 0.90 | ADORA2A (0.46) | ADORA2ACDK2CCNB2CCNE2CDK1 | |
| Formic Acid SCHEMBL7204951 | 0.89 | ADORA2A (0.50) | ADORA2ACDK2CCNB2CCNE2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610665-B1 | Treatment of inflammatory diseases, asthma or chronic obstructive pulmonary disease | SMITHKLINE BEECHAM CORPORATION | 2003-08-26 | — | — | US | claimed |
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | claimed |