Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | LSS | P48449 | 8/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7208527 | 1.00 | HTR2A (0.51) | HTR2AHTR2CLSSHTR1ADRD2 | |
| SCHEMBL7210829 | 0.89 | HTR2A (0.50) | HTR2AHTR2CLSSL3MBTL1 | |
| SCHEMBL7205789 | 0.89 | HTR2A (0.51) | HTR2AHTR2CLSSL3MBTL1CNR2 | |
| SCHEMBL7205786 | 0.89 | HTR2A (0.51) | HTR2AHTR2CLSSL3MBTL1CNR2 | |
| SCHEMBL7210826 | 0.89 | HTR2A (0.50) | HTR2AHTR2CLSSL3MBTL1 | |
| SCHEMBL7206982 | 0.89 | HTR2A (0.49) | HTR2AHTR2CLSSHTR1ADRD2 | |
| SCHEMBL7206987 | 0.89 | HTR2A (0.49) | HTR2AHTR2CLSSHTR1ADRD2 | |
| SCHEMBL7205049 | 0.89 | LSS (0.62) | HTR2AHTR2CLSSL3MBTL1 | |
| SCHEMBL7205048 | 0.89 | LSS (0.62) | HTR2AHTR2CLSSL3MBTL1 | |
| SCHEMBL7210651 | 0.88 | HTR2A (0.49) | HTR2AHTR2CLSSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |