⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545252 | 0.72 | — | — | |
| SCHEMBL28957994 | 0.68 | — | — | |
| SCHEMBL9812189 | 0.64 | — | — | |
| SCHEMBL5644679 | 0.64 | — | — | |
| SCHEMBL19322482 | 0.64 | — | — | |
| SCHEMBL1521758 | 0.64 | — | — | |
| SCHEMBL28392521 | 0.64 | — | — | |
| SCHEMBL8707543 | 0.64 | — | — | |
| SCHEMBL28559460 | 0.60 | — | — | |
| SCHEMBL7595068 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873613-B2 | Nano or macro material functionalization and self assembled construction mediated by tris(trimethylsilyl)silane | FUNCTIONALIZE, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| EP-3134479-A1 | NANO OR MACRO MATERIAL FUNCTIONALIZATION AND SELF ASSEMBLED CONSTRUCTION MEDIATED BY TRIS(TRIMETHYLSILYL)SILANE | Functionalize, Inc. (US) | 2017-03-01 | — | — | EP | disclosed |
| US-20160376152-A1 | NANO OR MACRO MATERIAL FUNCTIONALIZATION AND SELF ASSEMBLED CONSTRUCTION MEDIATED BY TRIS(TRIMETHYLSILYL)SILANE | FUNCTIONALIZE, INC. | 2016-12-29 | — | — | US | disclosed |
| WO-2015131160-A1 | NANO OR MACRO MATERIAL FUNCTIONALIZATION AND SELF ASSEMBLED CONSTRUCTION MEDIATED BY TRIS(TRIMETHYLSILYL)SILANE | FUNCTIONALIZE, INC. (US) | 2015-09-03 | — | — | WO | disclosed |
| EP-0970079-B1 | FARNESYL TRANSFERASE INHIBITING 1,8-ANNELATED QUINOLINONE DERIVATIVES SUBSTITUTED WITH N- OR C-LINKED IMIDAZOLES | JANSSEN PHARMACEUTICA NV (BE) | 2003-10-01 | — | — | EP | disclosed |
| US-6444812-B1 | SUCH AS 7-(3-CHLOROPHENYL)-9-((4-CHLOROPHENYL)-1H-IMIDAZOL-1-YLMETHYL)-2,3-DIHYDRO -1H,5H-BENZO(IJ) QUINOLIZIN-5-ONE; FOR FORMING ONCOGENES FOR SIGNALLING TRANSFORMATION OF TUMOR CELLS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-09-03 | — | — | US | disclosed |
| US-20020049327-A1 | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles | VENET MARC GASTON (FR) | 2002-04-25 | — | — | US | disclosed |
| US-6187786-B1 | ANTITUMOR AND ANTICARCINOGENIC AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-02-13 | — | — | US | disclosed |