Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 9/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6700811 | 0.92 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6700965 | 0.92 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| Hydrochloric Acid SCHEMBL7205066 | 0.85 | TLR7 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6702028 | 0.79 | TLR7 (0.47) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6697494 | 0.79 | TLR7 (0.47) | TLR7LMNAPOLBHRH2ADRA1D | |
| Hydrochloric Acid SCHEMBL6699305 | 0.79 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| Hydrochloric Acid SCHEMBL6704112 | 0.79 | TLR7 (0.46) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL6699123 | 0.73 | TLR7 (0.54) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL5360305 | 0.71 | TLR7 (0.60) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL4330880 | 0.70 | TLR7 (0.59) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339715-A2 | HETEROCYCLIC ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046193-A2 | HETEROCYCLIC ETHER SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-06-13 | — | — | WO | disclosed |