SCHEMBL7208909

SCHEMBL7208909

O=[N+]([O-])Nc1ccccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.49
LMNA P02545 3/20 0.49
ALDH1A1 P00352 2/20 0.49
HTT P42858 1/20 0.49
MAPT P10636 5/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HPGD P15428 3/20 0.43
PKM P14618 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KMT2A Q03164 4/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 3/20 0.41
TSHR P16473 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31374378 1.00 MAPK1 (0.49) MAPK1LMNAALDH1A1HTTMAPT
SCHEMBL309256 0.83 MEN1 (0.47) MAPK1LMNAALDH1A1HTTMAPT
SCHEMBL11568673 0.78 MAPT (0.35) MAPK1LMNAALDH1A1HTTMAPT
SCHEMBL28006025 0.76 HSP90AA1 (0.44) MAPK1LMNAALDH1A1HTTMAPT
SCHEMBL10610192 0.75 KMT2A (0.47) MAPK1MAPTL3MBTL1KMT2ACYP2C19
SCHEMBL11563326 0.75 TSHR (0.52) MAPK1LMNAALDH1A1HTTMAPT
SCHEMBL950729 0.74 MAPK1 (0.60) MAPK1ALDH1A1MAPTL3MBTL1PKM
SCHEMBL45337 0.74 MAPT (0.47) MAPK1LMNAALDH1A1MAPTL3MBTL1
SCHEMBL30335 0.74 NPC1 (0.49) MAPK1LMNAHTTMAPTL3MBTL1
SCHEMBL11045869 0.74 MEN1 (0.43) MAPK1LMNAALDH1A1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109803949-B Catalyst modification using alkali metal ions, alkaline earth metal ions or rare earth metal ions in the continuous liquid phase hydrogenation of nitro compounds 巴斯夫欧洲公司 2023-04-14 CN disclosed
US-11478727-B2 Difluoroacetic acid ion pairing reagent for high sensitivity, high resolution LC-MS of biomolecules and small molecules WATERS TECHNOLOGIES CORPORATION (US) 2022-10-25 US disclosed
US-20200261826-A1 DIFLUOROACETIC ACID ION PAIRING REAGENT FOR HIGH SENSITIVITY, HIGH RESOLUTION LC-MS OF BIOMOLECULES AND SMALL MOLECULES WATERS TECHNOLOGIES CORPORATION (US) 2020-08-20 US disclosed
CN-109608355-A A kind of synthesis technology of 2- amino -4- acetyl-anisidine 浙江闰土新材料有限公司 2019-04-12 CN disclosed
CN-106000075-B The purification absorption of chlorinated exhaust and circulation utilization method and device in benzene chloridization process 浙江闰土新材料有限公司 2018-10-26 CN disclosed
US-6617315-B1 Sugar-substituted benzimidazole derivatives are used for the treatment or prophylaxis of restenosis, particularly following angioplasty CHAMBERLAIN STANLEY DAWES (US) 2003-09-09 US disclosed
CN-1037548-Y To asphalt in additive used for carrying out marking and identifying Morton international stock co ltd 1998-02-25 CN disclosed
EP-0282852-B1 AZO DYES BAYER AG (DE) 1990-10-10 EP disclosed
EP-0282852-A2 Azo dyes BAYER AG (DE) 1988-09-21 EP disclosed
US-4296028-A Pyrazolonyl substituted disazo pigments BASF ITALIA SPA (IT) 1981-10-20 US disclosed
US-4269769-A Diazo compounds obtained by coupling acetoacetanilides with tetrazotized diaminobenzanilides AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) 1981-05-26 US disclosed
EP-0017769-A1 Dyestuffs of the thiazole series and their use BASF Aktiengesellschaft (DE) 1980-10-29 EP disclosed
US-4205988-A Photochromic method involving an aromatic amine ASAHI KASEI K. K. (JP) 1980-06-03 US disclosed
US-4023973-A PRINTING JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-05-17 US disclosed