Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 7/20 | 0.45 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211205 | 0.99 | LSS (0.43) | LSSFAAHTHRATHRBHTR2A | |
| SCHEMBL7211201 | 0.99 | LSS (0.43) | LSSFAAHTHRATHRBHTR2A | |
| SCHEMBL4803402 | 0.95 | LSS (0.43) | LSSFAAHTHRATHRBHTR2A | |
| SCHEMBL4803396 | 0.95 | LSS (0.43) | LSSFAAHTHRATHRBHTR2A | |
| SCHEMBL4803189 | 0.89 | LSS (0.48) | LSSFAAHTHRATHRB | |
| SCHEMBL4803192 | 0.89 | LSS (0.48) | LSSFAAHTHRATHRB | |
| SCHEMBL28941656 | 0.88 | LSS (0.57) | LSS | |
| SCHEMBL4803304 | 0.88 | LSS (0.57) | LSS | |
| SCHEMBL7205863 | 0.87 | LSS (0.49) | LSSFAAHACHE | |
| SCHEMBL7205855 | 0.87 | LSS (0.49) | LSSFAAHACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |