Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 20/20 | 0.72 |
| ▸ | CDK2 | P24941 | 20/20 | 0.72 |
| ▸ | CCNA1 | P78396 | 19/20 | 0.72 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.72 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.72 |
| ▸ | CDK1 | P06493 | 2/20 | 0.72 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.72 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.72 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.72 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.72 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6790291 | 0.85 | CCNA2 (0.71) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL6784144 | 0.85 | CCNA2 (0.71) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL6788293 | 0.85 | CCNA2 (0.71) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL6787929 | 0.83 | CCNA2 (1.00) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL3927344 | 0.83 | CCNA2 (1.00) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL1882254 | 0.83 | CCNA2 (1.00) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL6789599 | 0.83 | CCNA2 (0.66) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL6783831 | 0.83 | CCNA2 (0.66) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL6789793 | 0.83 | CCNA2 (0.66) | CCNA2CDK2CCNA1CCNB2CCNE2 | |
| SCHEMBL6783807 | 0.83 | CCNA2 (0.66) | CCNA2CDK2CCNA1CCNB2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345909-A1 | PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | Pharmacia Italia S.p.A. (IT) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002048114-A1 | PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA ITALIA S.P.A. (IT) | 2002-06-20 | — | — | WO | disclosed |