Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 14/20 | 1.00 |
| ▸ | PRKCA | P17252 | 4/20 | 0.78 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.66 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.66 |
| ▸ | CDK2 | P24941 | 6/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840521 | 1.00 | CDK1 (1.00) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5840524 | 1.00 | CDK1 (1.00) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5839065 | 0.91 | CDK1 (1.00) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5839069 | 0.91 | CDK1 (1.00) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5839489 | 0.91 | CDK1 (0.83) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5839495 | 0.91 | CDK1 (0.83) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5840461 | 0.91 | CDK1 (0.83) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL7210297 | 0.89 | CDK1 (1.00) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5840159 | 0.89 | CDK1 (1.00) | CDK1PRKCAPDGFRACCNE1CDK2 | |
| SCHEMBL5840162 | 0.89 | CDK1 (1.00) | CDK1PRKCAPDGFRACCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874846-B1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2003-04-02 | — | — | EP | disclosed |