Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 13/20 | 0.58 |
| ▸ | LIPC | P11150 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209424 | 1.00 | LSS (0.58) | LSSLIPCLIPGACHEMCHR1 | |
| SCHEMBL4806921 | 0.96 | LSS (0.58) | LSSLIPCLIPGACHEMCHR1 | |
| SCHEMBL4806926 | 0.96 | LSS (0.58) | LSSLIPCLIPGACHEMCHR1 | |
| SCHEMBL4799874 | 0.90 | LSS (0.57) | LSSLIPCLIPGMCHR1SLC6A5 | |
| SCHEMBL4799882 | 0.90 | LSS (0.57) | LSSLIPCLIPGMCHR1SLC6A5 | |
| SCHEMBL7205863 | 0.89 | LSS (0.49) | LSSACHE | |
| SCHEMBL7205855 | 0.89 | LSS (0.49) | LSSACHE | |
| SCHEMBL4804327 | 0.89 | LSS (0.55) | LSSLIPCLIPG | |
| SCHEMBL4804320 | 0.89 | LSS (0.55) | LSSLIPCLIPG | |
| SCHEMBL7210770 | 0.89 | LSS (0.50) | LSSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | claimed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | claimed |
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |