Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 7/20 | 0.42 |
| ▸ | FLT3 | P36888 | 5/20 | 0.42 |
| ▸ | FYN | P06241 | 5/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209948 | 0.87 | TSHR (0.52) | ALDH1A1HSD17B10FBP1TSHRNPSR1 | |
| SCHEMBL7208352 | 0.85 | TLR7 (0.41) | TLR7 | |
| SCHEMBL7209290 | 0.84 | TLR7 (0.40) | ALDH1A1HSD17B10TSHRNPSR1TLR7 | |
| SCHEMBL7209444 | 0.83 | TLR7 (0.38) | ALDH1A1TSHRNPSR1TLR7CDK9 | |
| SCHEMBL5730393 | 0.80 | TLR7 (0.55) | TLR7 | |
| SCHEMBL5732110 | 0.78 | ADORA2A (0.53) | ALDH1A1FBP1TSHR | |
| SCHEMBL7205474 | 0.77 | TSHR (0.45) | ALDH1A1HSD17B10TSHRNPSR1TLR7 | |
| SCHEMBL7210390 | 0.77 | TLR7 (0.60) | TLR7 | |
| SCHEMBL7209553 | 0.77 | TSHR (0.44) | ALDH1A1HSD17B10TSHRNPSR1TLR7 | |
| SCHEMBL7211567 | 0.76 | TSHR (0.44) | ALDH1A1HSD17B10TSHRNPSR1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |