Ethylene Glycol

Ethylene Glycol

SCHEMBL7209626

C=C.OCC1CCC(CO)CC1.OCCO

nearest known ligand 0.39

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.39
ESR2 Q92731 6/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
APLNR P35414 1/20 0.35
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL689586 0.93 ESR2 (0.42) ESR1ESR2CYP3A4CYP2C9APLNR
SCHEMBL297828 0.86 ESR2 (0.46) ESR1ESR2CYP3A4CYP2C9APLNR
SCHEMBL130642 0.86 ESR2 (0.46) ESR1ESR2CYP3A4CYP2C9APLNR
SCHEMBL1316560 0.86 ESR2 (0.46) ESR1ESR2CYP3A4CYP2C9APLNR
SCHEMBL2267415 0.86 ESR2 (0.46) ESR1ESR2CYP3A4CYP2C9APLNR
SCHEMBL4610 0.86
SCHEMBL27912 0.86 ESR2 (0.46) ESR1ESR2CYP3A4CYP2C9APLNR
Ethylene Glycol SCHEMBL6129164 0.83 ESR1 (0.34) ESR1ESR2CYP3A4CYP2C9CYP2D6
Phosphine SCHEMBL23581883 0.82 ESR1 (0.44) ESR1ESR2CYP3A4CYP2C9APLNR
SCHEMBL8744483 0.82 ESR1 (0.44) ESR1ESR2CYP3A4CYP2C9APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1958974-B1 UV HARDENING DISPERSIONS BASED ON POLYISOCYANTES COVESTRO DEUTSCHLAND AG (DE) 2020-04-08 EP disclosed
EP-0857749-B1 Cards, for recording information, of a thermoplastic resin composition TORAY INDUSTRIES (JP) 2003-07-16 EP disclosed
JP-2002128879-A POLYESTER AND ITS MOLDED BODY TEIJIN LTD 2002-05-09 JP disclosed