Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7208576 | 0.99 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7205215 | 0.91 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7210441 | 0.90 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7212615 | 0.86 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7205772 | 0.86 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7211531 | 0.86 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7377329 | 0.83 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7381260 | 0.81 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672386 | 0.81 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7205693 | 0.80 | MEN1 (0.43) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045849-B1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO CELTIQUE SA (LU) | 2003-07-02 | — | — | EP | claimed |