Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.82 |
| ▸ | HTR2A | P28223 | 8/20 | 0.56 |
| ▸ | HTR2C | P28335 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209665 | 1.00 | LSS (0.82) | LSSHTR2AHTR2C | |
| SCHEMBL7211570 | 0.99 | LSS (0.80) | LSSHTR2AHTR2C | |
| SCHEMBL7211566 | 0.99 | LSS (0.80) | LSSHTR2AHTR2C | |
| SCHEMBL4807767 | 0.94 | LSS (0.80) | LSSHTR2AHTR2C | |
| SCHEMBL4807775 | 0.94 | LSS (0.80) | LSSHTR2AHTR2C | |
| SCHEMBL7204701 | 0.88 | LSS (0.70) | LSSHTR2AHTR2C | |
| SCHEMBL7204697 | 0.88 | LSS (0.70) | LSSHTR2AHTR2C | |
| SCHEMBL4802084 | 0.88 | LSS (1.00) | LSSHTR2AHTR2C | |
| SCHEMBL4802774 | 0.88 | LSS (1.00) | LSSHTR2AHTR2C | |
| SCHEMBL4806053 | 0.88 | LSS (0.79) | LSSHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | claimed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | claimed |
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |