Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093719 | 1.00 | AR (0.48) | ARMALT1MAPTMAP3K8 | |
| SCHEMBL14033682 | 0.89 | AR (0.52) | AR | |
| SCHEMBL4041163 | 0.89 | AR (0.52) | AR | |
| SCHEMBL6212104 | 0.86 | AR (0.53) | ARMAPT | |
| SCHEMBL5097865 | 0.86 | AR (0.53) | ARMAPT | |
| SCHEMBL5090784 | 0.85 | AR (0.50) | AR | |
| SCHEMBL5088725 | 0.84 | AR (0.50) | ARMALT1MAPT | |
| SCHEMBL4224598 | 0.82 | AR (0.65) | AR | |
| SCHEMBL5092475 | 0.80 | AR (0.56) | AR | |
| SCHEMBL5098133 | 0.80 | AR (0.52) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1299385-A2 | FUSED CYCLIC MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2003-04-09 | — | — | EP | claimed |
| WO-2002000653-A2 | FUSED CYCLIC COMPOUNDS AS MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-03 | — | — | WO | claimed |