Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 12/20 | 0.60 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | ATF4 | P18848 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209751 | 1.00 | LSS (0.60) | LSSACHEATF4PTGER1PTGER4 | |
| SCHEMBL7209046 | 0.98 | LSS (0.60) | LSSACHEATF4PTGER1PTGER4 | |
| SCHEMBL7209051 | 0.98 | LSS (0.60) | LSSACHEATF4PTGER1PTGER4 | |
| SCHEMBL7209787 | 0.97 | LSS (0.59) | LSSACHEATF4PTGER1PTGER4 | |
| SCHEMBL7209793 | 0.97 | LSS (0.59) | LSSACHEATF4PTGER1PTGER4 | |
| SCHEMBL7203371 | 0.89 | LSS (0.72) | LSSACHE | |
| SCHEMBL7203375 | 0.89 | LSS (0.72) | LSSACHE | |
| SCHEMBL7204037 | 0.88 | LSS (0.74) | LSSACHE | |
| SCHEMBL7206527 | 0.88 | LSS (0.74) | LSSACHE | |
| SCHEMBL4804033 | 0.87 | LSS (0.64) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |