Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 10/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209778 | 1.00 | LSS (0.49) | LSSLTA4HACHEFAAHFDPS | |
| SCHEMBL7205855 | 0.97 | LSS (0.49) | LSSLTA4HACHEFAAHKDM4E | |
| SCHEMBL7205863 | 0.97 | LSS (0.49) | LSSLTA4HACHEFAAHKDM4E | |
| SCHEMBL7207582 | 0.90 | LSS (0.49) | LSSACHE | |
| SCHEMBL7207579 | 0.90 | LSS (0.49) | LSSACHE | |
| SCHEMBL7205040 | 0.90 | LSS (0.61) | LSSACHEFDPS | |
| SCHEMBL7205037 | 0.90 | LSS (0.61) | LSSACHEFDPS | |
| SCHEMBL7210770 | 0.89 | LSS (0.50) | LSSLTA4HACHE | |
| SCHEMBL7210766 | 0.89 | LSS (0.50) | LSSLTA4HACHE | |
| SCHEMBL7209424 | 0.88 | LSS (0.58) | LSSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |