Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.64 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | F13A1 | P00488 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | THPO | P40225 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211245 | 0.97 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL7214675 | 0.97 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL8962152 | 0.97 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL7209763 | 0.97 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL7210069 | 0.97 | PAOX (0.67) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL20561185 | 0.95 | PAOX (0.62) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL6892383 | 0.92 | PAOX (0.52) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL7214660 | 0.90 | PAOX (0.58) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL8962182 | 0.86 | PAOX (0.59) | PAOXGNAI3GNAO1GNAI1MAOA | |
| SCHEMBL7214695 | 0.85 | PAOX (0.64) | PAOXGNAI3GNAO1GNAI1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920434-A3 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0920434-B1 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | HOFFMANN LA ROCHE (CH) | 2002-10-16 | — | — | EP | disclosed |
| US-6060616-A | ANTITUMORS AGENTS; LEUKEMIA, OVARIAN CARCINOMA | HOFFMANN-LA ROCHE INC. (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0920434-A2 | BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998003518-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYMETHYLENE DERIVATIVES AS LIGANDS HAVING ANTITUMOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |